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 April 2015

 Volume 2  Issue 1

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Short Communication

Therapeutic Effect of Panax Notoginseng Saponins (PNS) on Hematoma Absorption Neurological Function Recovery in Hypertensive Intracerebral Hemorrhage Patients

Zhijian Luo, Nian Xiong* , Mingqing Xiang, Qiang Tu, Hua Wang , Xianling Cheng, Yi Huang, Tingting Hu, Dongzhu Li, Fei Li, Chengming Ke, Zhicheng Lin, Shaolian Zhu

Hypertensive intracerebral hemorrhage(HICH) leads to high mortality and disability, yet lacking widely approved clinical therapy. Here, we conducted a case-control study in patients with HICH to investigate the effect of panax notoginseng saponins (PNS), a well-known Chinese herbal, on hematoma absorption and neurological function recovery in HICH patients.


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Short Communication

Feasibility of High-Density EEG Mismatch Negativity Paradigm for Assessing Phoneme Processing in Preterm Infants

Karine Pelc*, Ana Maria Cebolla, Carlos Cevallos, Laurence Dewulf, Anne Britt Johansson, Guy Cheron, Bernard Dan

Owing to excellent time resolution and optimized spatial resolution related to increased number of recording electrodes, high-density electroencephalography allows localization of the sources of cortical activities evoked by specific stimulation. Here we evaluate the feasibility of a high-density EEG mismatch negativity of event-related potentials approach involving auditory cortical processing of phonemes in newborn infants born preterm (28 and 31 weeks’ gestation) in a routine clinical set-up. We recorded 64-channel EEG at term age.

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Research Article

The Acute Porphyrias: Still A Misdiagnosed Cause of Neurological Syndromes

Paolo Ventura*, Matteo Marcacci, Stefano Marchini

Porphyrias are a heterogeneous group of rare metabolic disorders, caused by a partial deficiency in one of the enzymes in the heme biosynthetic pathway.Four forms of porphyrias, also referred as the acute porphyrias [acute intermittent porphyria, hereditary coproporphyria, variegate porphyria and the very rare porphyria due to ALA-dehydratase deficit] may present clinically with recurrent and severe acute neurovisceral crises [acute porphyric attack (APA), including severe abdominal pain and moderate to severe symptoms due to involvement of both peripheral and central nervous system imputable to an accumulation in tissues and plasma of non-porphyrin heme precursors [α-aminolevulinic acid (ALA) and porphobilinogen (PBG)].

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